Successful desensitization to colistin in a Peruvian patient with cystic fibrosis

Authors

  • Liz Veramendi-Espinoza Servicio de Alergia. Hospital Nacional Edgardo Rebagliati Martins. Lima-Perú
  • Vladimir Espinoza-Ildefonso Servicio de Infectología. Hospital Nacional Edgardo Rebagliati Martins. Lima-Perú
  • Joel Calero Herrera Servicio de Alergia. Hospital Nacional Edgardo Rebagliati Martins. Lima-Perú
  • Juan Carlos Aldave Becerra Servicio de Alergia. Hospital Nacional Edgardo Rebagliati Martins. Lima-Perú

DOI:

https://doi.org/10.35434/rcmhnaaa.2023.162.1706

Keywords:

Cystic Fibrosis, Drug Hypersensitivity, Anti-Bacterial Agents, Colistin, Precision Medicine

Abstract

Introduction: Pharmacological desensitization induces a temporary hyposensitivity to the causative drug in patients with Immunoglobulin E-mediated drug reactions. Case of report: We present the case of a patient with respiratory exacerbation of cystic fibrosis who presented immediate hypersensitivity to colistin, an essential antibiotic for its treatment—both due to the sensitivity of the microorganism and the lack of availability of other drugs. The procedure was successfully performed in the Intensive Care Unit, and the patient completed the treatment schedule. Conclusion: Currently, the patient is undergoing specific treatment for his underlying disease and has not presented any new episodes of exacerbation or pneumonia.

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Author Biographies

Liz Veramendi-Espinoza, Servicio de Alergia. Hospital Nacional Edgardo Rebagliati Martins. Lima-Perú

1. Médico especialista en Inmunología y Alergia

Vladimir Espinoza-Ildefonso, Servicio de Infectología. Hospital Nacional Edgardo Rebagliati Martins. Lima-Perú

1. Médico especialista en Infectología y Medicina Tropical

Joel Calero Herrera, Servicio de Alergia. Hospital Nacional Edgardo Rebagliati Martins. Lima-Perú

1. Médico especialista en Inmunología y Alergia

Juan Carlos Aldave Becerra, Servicio de Alergia. Hospital Nacional Edgardo Rebagliati Martins. Lima-Perú

1. Médico especialista en Inmunología y Alergia

References

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Published

2023-06-22

How to Cite

1.
Veramendi-Espinoza L, Espinoza-Ildefonso V, Calero Herrera J, Aldave Becerra JC. Successful desensitization to colistin in a Peruvian patient with cystic fibrosis. Rev. Cuerpo Med. HNAAA [Internet]. 2023 Jun. 22 [cited 2024 May 20];16(2). Available from: http://www.cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/1706